Description

tert-Butylsulfamoyl Chloride is a specialized organosulfur reagent primarily used as a key sulfamoylating agent in synthetic organic chemistry. Its value lies in its role as a crucial building block for introducing the tert-butylsulfamoyl moiety, a valuable functional group in medicinal chemistry and material science. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries engaged in the development of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of sulfonamide-based drug candidates, including protease inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides where the tert-butylsulfamoyl group contributes to efficacy and selectivity.
• Fine Chemical Building Block: Employed in custom synthesis and research for creating complex molecules with tailored properties for material science applications.
• Protecting Group Chemistry: Serves as a reagent for introducing sulfamoyl protecting groups in multi-step synthetic routes.
• Chemical Research & Development: A valuable tool for academic and industrial R&D labs exploring new synthetic methodologies and reaction pathways.

Basic Information

Product Name	tert-Butylsulfamoyl Chloride
CAS No.	33581-95-2
Molecular Formula	C4H10ClNO2S
Molecular Weight	171.65 g/mol
Synonyms	N-(tert-Butyl)sulfamoyl Chloride; 2-Methyl-2-propanesulfonamide Chloride; tert-Butylaminosulfonyl Chloride; N-tert-Butylsulfamoyl Chloride; 1,1-Dimethylethylsulfamoyl Chloride; TBSC; t-BuSO2NCl
EINECS	Contact for details

Quality Control

Our tert-Butylsulfamoyl Chloride is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding synthetic applications. Each batch is analyzed using advanced techniques including HPLC, NMR, and titration to verify identity and potency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.