Description

4-Chloro-2-(Dichloromethyl)-1-Fluorobenzene is a versatile halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique substitution pattern, featuring chloro, dichloromethyl, and fluoro groups, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where its halogen atoms can be further functionalized.
• Material Science Precursor: Serves as a monomer or building block for the development of specialty polymers and liquid crystals.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution reactions to introduce complex aromatic fragments.
• Chemical Research & Development: Essential for medicinal chemistry programs and process chemistry optimization in R&D laboratories.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing halogenated dyes and specialty colorants.

Basic Information

Product Name	4-Chloro-2-(Dichloromethyl)-1-Fluorobenzene
CAS No.	33429-67-3
Molecular Formula	C7H4Cl3F
Molecular Weight	213.46 g/mol
Synonyms	1-Fluoro-4-chloro-2-(dichloromethyl)benzene; 2-(Dichloromethyl)-4-chloro-1-fluorobenzene; 4-Chloro-2-(dichloromethyl)fluorobenzene; 2,4-Dichlorobenzotrifluoride related intermediate; Benzene, 4-chloro-2-(dichloromethyl)-1-fluoro-; α,α,4-Trichloro-2-fluorotoluene
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(Dichloromethyl)-1-Fluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.