Description

2-Chloro-5-Fluorotoluene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents on the toluene ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluoromethyl or chlorotoluene backbone.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the halogenated aromatic core enhances biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a building block for specialty chemicals used in electronic displays and optoelectronic devices.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Negishi) and as a starting material for further functionalization in research and development.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of complex dyes and organic pigments.
• Polymer Modification: Used to introduce halogenated aromatic units into polymer chains to alter thermal and chemical resistance properties.

Basic Information

Item	Details
Product Name	2-Chloro-5-Fluorotoluene
CAS No.	33406-96-1
Molecular Formula	C7H6ClF
Molecular Weight	144.57 g/mol
Synonyms	1-Chloro-2-fluoro-5-methylbenzene; 2-Chloro-5-fluoromethylbenzene; 5-Fluoro-2-chlorotoluene; 2-Chloro-5-fluoro-1-methylbenzene; 2-Fluoro-5-chlorotoluene; 2-Chloro-5-fluorotoluol; 5-Chloro-2-fluorotoluene (isomer); Toluene, 2-chloro-5-fluoro-
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Fluorotoluene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee compliance with your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C (59°F and 77°F).

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (20°C)	~1.22 g/cm³
Boiling Point	~185-190 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.