Description

[(20R)-5β-Pregnane-3α,11β,20-Triyl]Tri(Oxy)]Tris(Trimethylsilane) CAS NO 33287-46-6 is a high-purity, trimethylsilyl-protected derivative of a pregnane steroid, serving as a critical advanced pharmaceutical intermediate and research-grade building block in organic synthesis. This compound is essential for researchers and manufacturers requiring precise chemical modifications to the steroid core structure, enabling the development of novel therapeutic agents and biochemical probes. It is primarily utilized in pharmaceutical R&D, academic research, and the synthesis of specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs) and drug candidates.
• Organic Synthesis Building Block: Used in research laboratories for the protection of hydroxyl groups and the construction of sophisticated molecular architectures.
• Biochemical Research: Employed in the study of steroid hormone pathways, receptor binding, and the development of labeled analogs for tracing and analysis.
• Fine Chemical Production: Integral to the manufacture of high-value, specialized chemicals used in life sciences and advanced material research.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical and contract research organizations.

Basic Information

Product Name	[(20R)-5β-Pregnane-3α,11β,20-Triyl]Tri(Oxy)]Tris(Trimethylsilane)
CAS No.	33287-46-6
Molecular Formula	C30H60O3Si3
Molecular Weight	553.05 g/mol
Synonyms	5β-Pregnane-3α,11β,20-triol, tris(trimethylsilyl) ether; 3α,11β,20-Tris(trimethylsiloxy)-5β-pregnane; Pregnane-3α,11β,20-triyl tris(trimethylsilyl) ether; (20R)-5β-Pregnane-3α,11β,20-triol tris(trimethylsilyl) ether; TMS-protected 5β-pregnane triol; Steroid TMS ether derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of [(20R)-5β-Pregnane-3α,11β,20-Triyl]Tri(Oxy)]Tris(Trimethylsilane) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.