Description

2,2,2-Trifluoro-1-(3-Pyridinyl)-1,1-Ethanediol is a high-value fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is essential for introducing the trifluoroethanol pharmacophore and pyridine moiety into target molecules, enabling the development of compounds with enhanced metabolic stability and binding affinity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and development of new active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the fluorine atoms improve lipophilicity and biological activity.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of fluorinated polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme mechanisms and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	2,2,2-Trifluoro-1-(3-Pyridinyl)-1,1-Ethanediol
CAS No.	33284-19-4
Molecular Formula	C7H6F3NO2
Molecular Weight	193.12 g/mol
Synonyms	2,2,2-Trifluoro-1-(pyridin-3-yl)ethane-1,1-diol; 3-Pyridyltrifluoromethylcarbinol; 1-(3-Pyridyl)-2,2,2-trifluoroethanol hydrate; α,α,α-Trifluoro-3-pyridinemethanol hydrate; 3-(1,1-Dihydroxy-2,2,2-trifluoroethyl)pyridine; 2,2,2-Trifluoro-1-(3-pyridyl)-1,1-ethanediol; TFPE Hydrate
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(3-Pyridinyl)-1,1-Ethanediol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.