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3β-[(2-o-β-D-Glucopyranosyl-3-o-Methyl-6-Deoxy-α-L-Glucopyranosyl)Oxy]-14-Hydroxy-5β-Card-20(22)-Enolide CAS NO 33279-55-9


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CAS No.:33279-55-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3β-[(2-o-β-D-Glucopyranosyl-3-o-Methyl-6-Deoxy-α-L-Glucopyranosyl)Oxy]-14-Hydroxy-5β-Card-20(22)-Enolide is a high-purity cardiac glycoside derivative, a compound class known for its significant biological activity. This specialized intermediate is critical for pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents targeting cardiovascular functions. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in advanced drug discovery and process chemistry.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of novel cardiac glycosides and related therapeutic compounds.
  • Biochemical Research: Used as a reference standard or active compound in studies of sodium-potassium ATPase (Na⁺/K⁺-ATPase) inhibition and cardiac pharmacology.
  • Drug Discovery: Serves as a core scaffold for the development of new drugs targeting heart failure and certain arrhythmias.
  • Analytical Standard: Employed in HPLC, LC-MS, and other analytical methods for method development, validation, and quality control of related substances.
  • Process Chemistry: Used in the scale-up and optimization of synthetic routes for complex natural product derivatives.

Basic Information

Product Name 3β-[(2-o-β-D-Glucopyranosyl-3-o-Methyl-6-Deoxy-α-L-Glucopyranosyl)Oxy]-14-Hydroxy-5β-Card-20(22)-Enolide
CAS No. 33279-55-9
Molecular Formula C₃₆H₅₈O₁₄
Molecular Weight 706.84 g/mol
Synonyms 14-Hydroxy-3β-[(2-O-β-D-glucopyranosyl-3-O-methyl-6-deoxy-α-L-glucopyranosyl)oxy]-5β-card-20(22)-enolide; 3β-[(2-O-β-D-Glucopyranosyl-3-O-methyl-6-deoxy-α-L-glucopyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide; Desglucouzarin; Uzarigenin 3-O-[2-O-β-D-glucopyranosyl-3-O-methyl-6-deoxy-α-L-glucopyranoside]; A cardiac glycoside aglycone derivative.
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Quality Control

Our 3β-[(2-o-β-D-Glucopyranosyl-3-o-Methyl-6-Deoxy-α-L-Glucopyranosyl)Oxy]-14-Hydroxy-5β-Card-20(22)-Enolide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 2.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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