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3β-[(2-o-β-D-Glucopyranosyl-3-o-Methyl-6-Deoxy-α-L-Glucopyranosyl)Oxy]-14-Hydroxy-5β-Card-20(22)-Enolide CAS NO 33279-55-9
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CAS No.:33279-55-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3β-[(2-o-β-D-Glucopyranosyl-3-o-Methyl-6-Deoxy-α-L-Glucopyranosyl)Oxy]-14-Hydroxy-5β-Card-20(22)-Enolide is a high-purity cardiac glycoside derivative, a compound class known for its significant biological activity. This specialized intermediate is critical for pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents targeting cardiovascular functions. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in advanced drug discovery and process chemistry.
Application
- Pharmaceutical Intermediate: A key building block in the synthesis of novel cardiac glycosides and related therapeutic compounds.
- Biochemical Research: Used as a reference standard or active compound in studies of sodium-potassium ATPase (Na⁺/K⁺-ATPase) inhibition and cardiac pharmacology.
- Drug Discovery: Serves as a core scaffold for the development of new drugs targeting heart failure and certain arrhythmias.
- Analytical Standard: Employed in HPLC, LC-MS, and other analytical methods for method development, validation, and quality control of related substances.
- Process Chemistry: Used in the scale-up and optimization of synthetic routes for complex natural product derivatives.
Basic Information
| Product Name | 3β-[(2-o-β-D-Glucopyranosyl-3-o-Methyl-6-Deoxy-α-L-Glucopyranosyl)Oxy]-14-Hydroxy-5β-Card-20(22)-Enolide |
| CAS No. | 33279-55-9 |
| Molecular Formula | C₃₆H₅₈O₁₄ |
| Molecular Weight | 706.84 g/mol |
| Synonyms | 14-Hydroxy-3β-[(2-O-β-D-glucopyranosyl-3-O-methyl-6-deoxy-α-L-glucopyranosyl)oxy]-5β-card-20(22)-enolide; 3β-[(2-O-β-D-Glucopyranosyl-3-O-methyl-6-deoxy-α-L-glucopyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide; Desglucouzarin; Uzarigenin 3-O-[2-O-β-D-glucopyranosyl-3-O-methyl-6-deoxy-α-L-glucopyranoside]; A cardiac glycoside aglycone derivative. |
| EINECS | Contact for details |
Quality Control
Our 3β-[(2-o-β-D-Glucopyranosyl-3-o-Methyl-6-Deoxy-α-L-Glucopyranosyl)Oxy]-14-Hydroxy-5β-Card-20(22)-Enolide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to reference spectrum |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 2.0% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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