Description

4-Chloro-3-Pyridine-Sulfonyl-Chloride is a high-purity, reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, enabling the efficient introduction of both the 4-chloropyridine moiety and a reactive sulfonyl chloride group into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients, intermediates, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require the specific pyridine-sulfonyl scaffold.
• Chemical Research & Development: A versatile reagent for constructing complex heterocyclic compounds and exploring new reaction pathways in medicinal chemistry.
• Material Science: Potential building block for functional polymers or ligands in catalytic systems.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing specialized intermediates for clients.

Basic Information

Product Name	4-Chloro-3-Pyridine-Sulfonyl-Chloride
CAS No.	33263-44-4
Molecular Formula	C6H3Cl2NO2S
Molecular Weight	232.06 g/mol
Synonyms	3-Pyridinesulfonyl chloride, 4-chloro-; 4-Chloro-3-pyridinesulfonyl chloride; 4-Chloropyridine-3-sulfonyl chloride; 4-Chloro-3-sulfonylchloropyridine; 33263-44-4; 4-Chloro-pyridine-3-sulfonyl chloride; 4-Chloro-3-pyridylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Pyridine-Sulfonyl-Chloride is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.