Description

4-Chloro-3-(Trifluoromethyl)Benzenesulfonyl Chloride is a high-value, multi-functional chemical intermediate characterized by its reactive sulfonyl chloride and halogenated aromatic structure. This compound matters for its critical role in synthesizing advanced molecules, particularly in the pharmaceutical and agrochemical sectors, where it serves as a key building block for sulfonamides and other active ingredients. Industrial buyers in fine chemical synthesis, crop protection R&D, and material science need this reagent for its ability to introduce the sulfonyl moiety and enable further functionalization, driving innovation in end-product development.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of sulfonamide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced bioactivity.
• Dyestuff and Pigment Production: Serves as an intermediate for creating specialized sulfonated dyes and colorants.
• Polymer and Material Science: Acts as a monomer or modifying agent for engineering polymers and advanced materials with specific surface properties.
• Chemical Research & Development: Employed in organic synthesis for introducing the benzenesulfonyl group and for further nucleophilic substitution reactions.
• Liquid Crystal and Electronic Chemical Intermediate: Used in the synthesis of components for display materials and other electronic applications.

Basic Information

Product Name	4-Chloro-3-(Trifluoromethyl)Benzenesulfonyl Chloride
CAS No.	32333-53-2
Molecular Formula	C7H3Cl2F3O2S
Molecular Weight	279.06 g/mol
Synonyms	4-Chloro-3-(trifluoromethyl)benzenesulfonyl chloride; 4-Chloro-alpha,alpha,α-trifluoro-m-toluenesulfonyl chloride; 3-Trifluoromethyl-4-chlorobenzenesulfonyl chloride; 4-Chloro-3-trifluoromethylphenylsulfonyl chloride; 1-Chloro-4-(chlorosulfonyl)-2-(trifluoromethyl)benzene; m-Trifluoromethyl-p-chlorobenzenesulfonyl chloride; Benzenesulfonyl chloride, 4-chloro-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-(Trifluoromethyl)Benzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent, keep the container tightly sealed under an inert atmosphere if necessary and away from moisture, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.