Description

Prostaglandins E2 Methyl Ester CAS NO 31753-17-0 is a methylated derivative of Prostaglandin E2 (PGE2), a key bioactive lipid mediator. This ester form offers enhanced stability and altered lipophilicity, making it a valuable intermediate and research tool for studying prostaglandin pathways and developing novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on inflammation, reproduction, and oncology research.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of more complex prostaglandin analogs and drug candidates.
• Biochemical Research: Used as a stable reference standard and probe to investigate the role of PGE2 in cellular signaling, inflammation, and pain pathways.
• Drug Discovery & Development: Serves as a building block for modifying the prostaglandin structure to improve pharmacokinetic properties like metabolic stability and membrane permeability.
• Academic Studies: Employed in laboratory experiments to understand reproductive physiology, cardiovascular function, and immune response modulation.
• Analytical Standard: Used for method development, calibration, and quantification in HPLC, LC-MS, and other analytical techniques.

Basic Information

Product Name	Prostaglandins E2 Methyl Ester
CAS No.	31753-17-0
Molecular Formula	C₂₁H₃₄O₅
Molecular Weight	366.5 g/mol
Synonyms	PGE2 Methyl Ester; Methyl PGE2; (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic Acid Methyl Ester; Dinoprostone Methyl Ester; Prostaglandin E2 Methyl Ester; 9-Oxo-11α,15S-dihydroxy-prosta-5,13-dien-1-oic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Prostaglandins E2 Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing specific results for purity, identity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.