Description

2-Fluoropyrimidine is a versatile fluorinated heterocyclic building block essential for advanced organic synthesis. Its value lies in the introduction of a fluorine atom into complex molecular architectures, which can dramatically alter the physical, chemical, and biological properties of target compounds. This high-purity intermediate is critically needed by R&D and production teams in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated nucleoside analogs, antiviral agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in creating novel fluorinated pesticides and herbicides with enhanced efficacy and environmental profiles.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers and liquid crystals.
• Chemical Research & Development: A fundamental reagent in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies.
• Fluorine Chemistry: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the pyrimidine moiety.
• Diagnostic Agent Development: Potential use in synthesizing radiolabeled probes or contrast agents for imaging.

Basic Information

Product Name	2-Fluoropyrimidine
CAS No.	31575-35-6
Molecular Formula	C4H3FN2
Molecular Weight	98.08 g/mol
Synonyms	2-Fluoropyrimidine; Pyrimidine, 2-fluoro-; 2-Fluoro-1,3-diazine; Fluoropyrimidine; 31575-35-6; FC1=NC=NC=C1; 2-Fluor-1,3-diazin
EINECS	Contact for details

Quality Control

Our 2-Fluoropyrimidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high chemical purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use and stored away from heat and ignition sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density	~1.25 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.