Description

4-Hydroxy-2-Phenyl-6-Quinolinesulfonic Acid Fluoride is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines a sulfonic acid fluoride moiety with a quinoline core, making it a valuable precursor for creating complex molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel quinoline-based drug candidates, including potential antimicrobials and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides that leverage the bioactive quinoline scaffold.
• Material Science: Serves as a precursor for creating functional dyes, fluorescent probes, and advanced polymeric materials due to its conjugated system.
• Chemical Biology: The reactive sulfonyl fluoride group makes it suitable for activity-based protein profiling (ABPP) and the development of covalent enzyme inhibitors.
• Organic Synthesis: Employed as a versatile intermediate in cross-coupling reactions and for introducing the sulfonyl fluoride functional group into target molecules.

Basic Information

Product Name	4-Hydroxy-2-Phenyl-6-Quinolinesulfonic Acid Fluoride
CAS No.	31241-71-1
Molecular Formula	C₁₅H₁₀FNO₄S
Molecular Weight	319.31 g/mol
Synonyms	6-Quinolinesulfonyl fluoride, 4-hydroxy-2-phenyl-; 2-Phenyl-4-hydroxy-6-quinolinesulfonyl fluoride; 4-Hydroxy-2-phenylquinoline-6-sulfonyl fluoride; 4-Hydroxy-2-phenylquinoline-6-sulfonic acid fluoride; Phenylhydroxyquinolinesulfonyl fluoride
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-2-Phenyl-6-Quinolinesulfonic Acid Fluoride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.