Description

2-Methyl-5-(Trifluoromethyl)Pyridine is a versatile fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of the electron-deficient pyridine ring and the robust trifluoromethyl group, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to create novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anti-inflammatory, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in fine chemical and material science applications.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and electronic materials that require specific fluorine-containing motifs.
• Chemical Biology Probes: Utilized as a building block for fluorinated probes and tags in diagnostic and bio-imaging research.

Basic Information

Product Name	2-Methyl-5-(Trifluoromethyl)Pyridine
CAS No.	31181-54-1
Molecular Formula	C7H6F3N
Molecular Weight	161.12 g/mol
Synonyms	5-(Trifluoromethyl)-2-picoline; 2-Picoline, 5-(trifluoromethyl)-; 2-Methyl-5-(trifluoromethyl)pyridine; 5-Trifluoromethyl-2-methylpyridine; α,α,α-Trifluoro-6-methyl-3-pyridinemethanol (related); 2-Methyl-5-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all commercial shipments, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and fluorides. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.