Description

2-Chloro-5-Fluoropyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chlorine and fluorine substituents, makes it a highly valuable intermediate for introducing specific reactivity and physicochemical properties into target molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to construct complex active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infective agents.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and functional polymers.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for fine chemical and custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Chloro-5-Fluoropyridine
CAS No.	31031-51-6
Molecular Formula	C5H3ClFN
Molecular Weight	131.54 g/mol
Synonyms	5-Fluoro-2-chloropyridine; 2-Chloro-5-fluoropyridine; 5-Fluoro-2-pyridinyl chloride; 2-Chloro-5-fluoro-pyridine; 31031-51-6; 2-Pyridinyl, 2-chloro-5-fluoro-; 5-Fluoropyridine, 2-chloro-
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-Fluoropyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by GC, HPLC, and NMR.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended long-term storage temperature is 2-8°C. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Purity (HPLC)	≥ 97.5%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.