Description

4-Quinolinecarboxylic Acid, 6-Fluoro-2-(Trifluoromethyl)- is a high-value fluorinated quinoline derivative, a key building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl groups, makes it indispensable for modulating the physicochemical properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced metabolic stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in oncology, anti-infective, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used to develop new generations of herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Serves as a building block for advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Fluorine Chemistry: An essential reagent for introducing fluorine-containing motifs into complex molecules, a common strategy in modern medicinal chemistry.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and structure-activity relationship (SAR) studies.

Basic Information

Product Name	4-Quinolinecarboxylic Acid, 6-Fluoro-2-(Trifluoromethyl)-
CAS No.	31009-06-0
Molecular Formula	C11H5F4NO2
Molecular Weight	259.16 g/mol
Synonyms	6-Fluoro-2-(trifluoromethyl)quinoline-4-carboxylic acid; 6-Fluoro-2-trifluoromethyl-4-quinolinecarboxylic acid; 4-Quinolinecarboxylic acid, 6-fluoro-2-(trifluoromethyl)-; 2-(Trifluoromethyl)-6-fluoroquinoline-4-carboxylic acid; 6-Fluoro-2-(trifluoromethyl)-4-quinolinecarboxylic acid; 31009-06-0; 6-Fluoro-2-trifluoromethylquinoline-4-carboxylic acid
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Every batch of 4-Quinolinecarboxylic Acid, 6-Fluoro-2-(Trifluoromethyl)- is analyzed to ensure it meets the high-purity standards required for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. Our quality system is designed to support cGMP and ISO guidelines for traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.