Description

Cyclopiazonic Acid Imine is a specific derivative of the mycotoxin cyclopiazonic acid, characterized by its imine functional group. This compound is of significant interest in biochemical and pharmacological research due to its role as a potent and specific inhibitor of the sarcoplasmic/endoplasmic reticulum Ca²⁺-ATPase (SERCA) pump. It serves as a critical research tool for scientists and institutions studying calcium signaling, muscle physiology, and cellular energy metabolism. The high-purity material is essential for ensuring reproducible and reliable experimental results in these advanced research fields.

Application

• Biochemical Research: Primary use as a selective inhibitor of SERCA pumps to study intracellular calcium homeostasis and signaling pathways.
• Pharmacological Studies: Investigation of calcium-dependent processes in cell models, including apoptosis, muscle contraction, and neurotransmitter release.
• Toxicology Research: Used as a reference standard or active agent in studies related to mycotoxin exposure and its biological effects.
• Enzyme Mechanism Studies: Tool compound for probing the structure and function of P-type ATPase enzymes.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in cell biology and physiology.
• Drug Discovery: Potential use in screening assays to identify novel modulators of calcium transport for therapeutic intervention.

Basic Information

Product Name	Cyclopiazonic Acid Imine
CAS No.	31008-94-3
Molecular Formula	C₂₀H₂₀N₂O₃
Molecular Weight	336.39 g/mol
Synonyms	Cyclopiazonic acid imine; α-Cyclopiazonic acid imine; CPA imine; 3,12-Dihydro-6-hydroxy-1,11-dimethyl-8,15-dioxo-1H,11H-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-3-acetonitrile; (3S,12S)-3,12-Dihydro-6-hydroxy-1,11-dimethyl-8,15-dioxo-1H,11H-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-3-acetonitrile
EINECS	Contact for details

Quality Control

Our Cyclopiazonic Acid Imine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS). A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and test results. We support research compliance and traceability requirements for global institutions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability. For long-term storage, consider storing under inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.