Description

Hexakis(6-Amino-6-Deoxy)-α-Cyclodextrin is a chemically modified derivative of α-cyclodextrin where all six primary hydroxyl groups are substituted with amino functionalities. This structural modification imparts a cationic character and enhanced molecular recognition properties, making it a highly valuable tool for supramolecular chemistry and pharmaceutical applications. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors for drug delivery, chiral separation, and as a building block for advanced materials.

Application

• Drug Delivery Systems: Acts as a cationic host molecule to form inclusion complexes, improving the solubility, stability, and bioavailability of poorly soluble active pharmaceutical ingredients (APIs).
• Chiral Separation & Analysis: Serves as a chiral selector or stationary phase modifier in capillary electrophoresis (CE) and high-performance liquid chromatography (HPLC) for the separation of enantiomers.
• Gene Delivery: Investigated as a component in non-viral vectors for gene therapy due to its ability to condense nucleic acids and facilitate cellular uptake.
• Catalysis & Sensor Development: Used as a scaffold or receptor in the design of artificial enzymes (enzyme mimics) and chemical sensors for molecular recognition.
• Material Science: Functions as a building block for constructing functionalized polymers, dendrimers, and nano-assemblies with tailored surface properties.
• Protein Stabilization & Refolding: Aids in the stabilization of proteins and assists in the refolding of denatured proteins in bioprocessing.

Basic Information

Product Name	Hexakis(6-Amino-6-Deoxy)-α-Cyclodextrin
CAS No.	30899-95-7
Molecular Formula	C36H60N6O24
Molecular Weight	972.89 g/mol
Synonyms	6A,6B,6C,6D,6E,6F-Hexaamino-6A,6B,6C,6D,6E,6F-hexadeoxy-α-cyclodextrin; 6-Peramino-α-cyclodextrin; α-Cyclodextrin, 6-amino-6-deoxy-, hexakis-; Heptakis(6-amino-6-deoxy)-α-cyclodextrin (common misnomer); Amino-α-CD; Cationic α-Cyclodextrin; 6-NH2-α-CD
EINECS	Contact for details

Quality Control

Our Hexakis(6-Amino-6-Deoxy)-α-Cyclodextrin is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.