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All-Amino β-Cyclodextrin CAS NO 30754-24-6


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CAS No.:30754-24-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

All-Amino β-Cyclodextrin is a chemically modified derivative of β-cyclodextrin where primary hydroxyl groups are substituted with amino functionalities. This modification significantly enhances its molecular encapsulation capabilities and water solubility, making it a superior host molecule for forming inclusion complexes with a wide range of guest compounds. It is a critical advanced material for researchers and formulators in the pharmaceutical, agrochemical, and specialty chemical industries seeking to improve the solubility, stability, and bioavailability of active ingredients.

Application

  • Pharmaceutical Formulation: As a solubility enhancer and stabilizer for poorly water-soluble drugs, improving bioavailability in oral and injectable formulations.
  • Drug Delivery Systems: For constructing targeted and controlled-release systems, leveraging the amino groups for further functionalization or pH-responsive release.
  • Catalyst & Ligand Support: Serving as a chiral scaffold or support material in asymmetric synthesis and catalysis due to its well-defined cavity and modifiable amino groups.
  • Analytical Chemistry: Used as a chiral selector or stationary phase modifier in capillary electrophoresis (CE) and high-performance liquid chromatography (HPLC) for enantiomer separation.
  • Agrochemical Enhancement: To encapsulate pesticides or herbicides, enhancing their stability, reducing volatility, and improving rainfastness.
  • Cosmetic & Personal Care: For entrapping fragrances, vitamins, or unstable active ingredients in creams and lotions to control release and increase shelf-life.
  • Environmental Remediation: As an adsorbent material functionalized for the selective removal of heavy metal ions or organic pollutants from wastewater.
  • Research & Development: A versatile building block in supramolecular chemistry for creating novel host-guest complexes and functional materials.

Basic Information

Item Details
Product Name All-Amino β-Cyclodextrin
CAS No. 30754-24-6
Molecular Formula C42H70N7O35
Molecular Weight Approx. 1293.1 g/mol
Synonyms Heptakis(6-amino-6-deoxy)-β-cyclodextrin; 6A,6B,6C,6D,6E,6F,6G-Heptaamino-6A,6B,6C,6D,6E,6F,6G-heptadeoxy-β-cyclodextrin; 6-Peramino-β-cyclodextrin; Amino-β-CD; NH2-β-CD; β-Cyclodextrin, amino derivative; Fully Amine-Substituted β-Cyclodextrin
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Quality Control

Our All-Amino β-Cyclodextrin is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and elemental analysis, to ensure consistent identity, purity, and substitution degree. Certificates of Analysis (COA) with detailed batch-specific results are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize moisture absorption.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 95.0%
Degree of Substitution (NMR) ~7.0 (Theoretical)
Water Content (KF) ≤ 5.0%
Residue on Ignition ≤ 0.5%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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