Description

1-Acetyl-5-Bromo-2,3-Dihydro-1H-Indole-7-Sulfonyl Chloride is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. Its core value lies in its reactive sulfonyl chloride and bromo-substituted indole scaffold, enabling precise molecular construction. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds with potential biological activity, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated indole structure.
• Material Science: Serves as a monomer or cross-linking agent in the creation of specialty polymers and advanced organic materials.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling or modifying biomolecules due to the electrophilic sulfonyl chloride group.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, multi-step transformations.
• Academic & Industrial R&D: Fundamental research tool for exploring new synthetic methodologies and reaction pathways in organic chemistry.

Basic Information

Product Name	1-Acetyl-5-Bromo-2,3-Dihydro-1H-Indole-7-Sulfonyl Chloride
CAS No.	30691-46-4
Molecular Formula	C10H9BrClNO3S
Molecular Weight	338.60 g/mol
Synonyms	5-Bromo-1-acetyl-2,3-dihydro-1H-indole-7-sulfonyl chloride; 7-(Chlorosulfonyl)-5-bromo-1-acetyl-2,3-dihydroindole; 1H-Indole-7-sulfonyl chloride, 1-acetyl-5-bromo-2,3-dihydro-; 5-Bromo-1-acetylindoline-7-sulfonyl chloride; 1-Acetyl-5-bromoindoline-7-sulfonyl chloride; 5-Bromo-1-acetyl-2,3-dihydroindole-7-sulfonyl chloride; ABDISC; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing all critical parameters are available upon request, providing full traceability and supporting your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.