Description

n-Nitroso-L-Hydroxyproline is a specialized nitrosated derivative of the amino acid L-hydroxyproline. This compound is of significant interest in biochemical and pharmaceutical research, particularly in studies related to nitrosation processes and collagen metabolism. It serves as a critical intermediate and reference standard for researchers and manufacturers in the life sciences sector, including those developing analytical methods or investigating protein modifications.

Application

• Biochemical Research Intermediate: Used as a key synthetic precursor or reference compound in studies of nitrosation and its biological effects.
• Pharmaceutical Reference Standard: Employed as a high-purity analytical standard for method development, validation, and quality control in drug discovery and development.
• Metabolic Pathway Studies: Applied in research focused on collagen biosynthesis, degradation, and the role of modified amino acids.
• Analytical Chemistry: Utilized in the development and calibration of chromatographic (e.g., HPLC, LC-MS) and spectroscopic analytical techniques.
• Academic & Institutional Research: Serves as a reagent for fundamental chemical and biological research in universities and government laboratories.

Basic Information

Product Name	n-Nitroso-L-Hydroxyproline
CAS No.	30310-80-6
Molecular Formula	C5H8N2O4
Molecular Weight	160.13 g/mol
Synonyms	L-Hydroxyproline, N-nitroso-; N-Nitrosohydroxyproline; (2S,4R)-4-Hydroxy-1-nitrosopyrrolidine-2-carboxylic acid; Nitrosohydroxyproline; 1-Nitroso-4-hydroxy-L-proline; 4-Hydroxy-1-nitrosoproline; NSC 163044
EINECS	Contact for details

Quality Control

Our n-Nitroso-L-Hydroxyproline is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant Good Laboratory Practice (GLP) and quality standards for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystals
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.