Description

Hex-5-Enylmagnesium Bromide 0.5M in THF is a high-purity Grignard reagent solution, specifically engineered for use as a critical building block in advanced organic synthesis. This compound is valued for its ability to introduce a terminal hex-5-enyl group, enabling efficient carbon-carbon bond formation in complex molecular architectures. It is an essential reagent for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries seeking to create novel compounds with specific alkenyl functionalities.

Application

• Pharmaceutical Intermediates: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing alkenyl side chains in drug discovery and development.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators requiring specific alkene-containing structures.
• Specialty Polymer & Material Science: Serves as a monomer or functionalization agent in the creation of novel polymers, liquid crystals, and advanced organic materials.
• Fine Chemical Manufacturing: Employed in multi-step synthetic routes for producing complex fragrance, flavor, and dye intermediates.
• Cross-Coupling Reactions: Acts as a nucleophile in transition metal-catalyzed cross-coupling reactions (e.g., Kumada coupling) to form new C-C bonds.
• Academic & Industrial R&D: A fundamental tool for research chemists exploring new synthetic methodologies and reaction pathways in organic chemistry.

Basic Information

Product Name	Hex-5-Enylmagnesium Bromide 0.5M in THF
CAS No.	30043-41-5
Molecular Formula	C6H11BrMg
Molecular Weight	163.36 g/mol (for C6H11BrMg)
Synonyms	5-Hexenylmagnesium bromide; 1-Buten-4-ylmagnesium bromide; 5-Hexen-1-ylmagnesium bromide; (5-Hexenyl)magnesium bromide; Grignard reagent 5-hexenylMgBr; Hex-5-en-1-ylmagnesium bromide; 30043-41-5; Magnesium, bromo(5-hexen-1-yl)-
EINECS	Contact for details

Quality Control

Our Hex-5-Enylmagnesium Bromide 0.5M in THF is manufactured under stringent quality systems to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay/concentration, titration against a standard, and verification of solution integrity. We adhere to cGMP principles where applicable, and our quality commitment supports compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. Due to its highly volatile and hygroscopic (moisture-sensitive) nature, the solution must be kept sealed and handled under anhydrous conditions. Recommended storage temperature is 2-8°C. Keep away from heat, sparks, open flames, and incompatible materials such as water, acids, and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to light yellow solution
Concentration (by Titration)	0.5 M in THF (± 0.05 M)
Assay (as C6H11BrMg)	Min. 95%
Identification (IR)	Conforms to structure
Water Content (Karl Fischer)	< 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.