Description

Acrylophenone, 2-Fluoro-2-Methyl- (8Ci) is a specialized fluorinated acrylophenone derivative, identified by CAS NO 30005-16-4, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an acryloyl and a fluorine-substituted methyl group, makes it a valuable precursor for introducing fluorinated motifs into target molecules, which is essential for modulating their physical, chemical, and biological properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications requiring precise molecular engineering.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated active pharmaceutical ingredients (APIs), potentially enhancing metabolic stability and bioavailability.
• Agrochemical Research: Used in the synthesis of novel fluorinated herbicides, pesticides, and plant growth regulators.
• Material Science: Building block for fluorinated monomers in the production of specialty polymers with unique surface properties, chemical resistance, or optical characteristics.
• Liquid Crystal & OLED Materials: Precursor for fluorinated components in electronic display and lighting materials.
• Cross-coupling Reactions: Serves as an electrophilic partner in various metal-catalyzed cross-coupling reactions to construct complex molecular architectures.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in fluorine chemistry and novel reaction pathway exploration.

Basic Information

Product Name	Acrylophenone, 2-Fluoro-2-Methyl- (8Ci)
CAS No.	30005-16-4
Molecular Formula	C10H9FO
Molecular Weight	164.18 g/mol
Synonyms	2-Fluoro-2-methylacrylophenone; 1-Propen-1-one, 2-fluoro-2-methyl-1-phenyl-; 2-Fluoro-2-methyl-1-phenyl-1-propen-1-one; 2-Methyl-2-fluoroacrylophenone; α-Fluoro-α-methylstyryl methyl ketone; 2-Fluoro-2-methylpropiophenone (related); Fluorinated acrylophenone derivative
EINECS	Contact for details

Quality Control

Our Acrylophenone, 2-Fluoro-2-Methyl- is produced and handled under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as assay (by HPLC or GC), impurity profile, and physical characteristics. Our quality commitment supports R&D and scale-up processes where reliable material properties are non-negotiable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Due to its light-sensitive nature and reactivity as a fluoride/strong alkali-sensitive compound, prolonged exposure to light or incompatible materials should be avoided. Keep away from heat and ignition sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 95.0%
Purity (by GC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.