Description

2-Fluoroisonicotinonitrile is a versatile fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a nitrile group on the pyridine ring, makes it a high-value intermediate for constructing complex molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Building block for developing new generation herbicides, fungicides, and insecticides with improved efficacy.
• Ligand and Catalyst Development: Used to create novel ligands for transition metal catalysis and organocatalysts.
• Material Science Research: Intermediate in the production of specialty polymers, liquid crystals, and electronic materials.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and development candidates.

Basic Information

Product Name	2-Fluoroisonicotinonitrile
CAS No.	3939-14-8
Molecular Formula	C6H3FN2
Molecular Weight	122.10 g/mol
Synonyms	2-Fluoropyridine-4-carbonitrile; 4-Cyano-2-fluoropyridine; 2-Fluoro-4-cyanopyridine; IsoNicotinonitrile, 2-fluoro-; 2-Fluoro-4-pyridinecarbonitrile; 3939-14-8; 2-Fluoropyridin-4-yl cyanide
EINECS	Contact for details

Quality Control

Our 2-Fluoroisonicotinonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation by FT-IR and NMR, and residual solvent analysis. A Certificate of Analysis (COA) is supplied with each batch, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.