Description

3-Cyano-2-Fluoropyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both cyano and fluorine substituents, enables precise molecular modifications essential for developing novel compounds. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the creation of novel organic electronic materials, liquid crystals, and polymers where its electronic properties are advantageous.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and molecular probes in diagnostic and bio-imaging applications.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Cyano-2-Fluoropyridine
CAS No.	3939-13-7
Molecular Formula	C6H3FN2
Molecular Weight	122.10 g/mol
Synonyms	2-Fluoro-3-cyanopyridine; 2-Fluoro-3-pyridinecarbonitrile; 3-Pyridinecarbonitrile, 2-fluoro-; 2-Fluoronicotinonitrile; 3-Cyano-2-fluoropyridine; 2-Fluoropyridine-3-carbonitrile; 2-Fluoro-3-cyano-pyridine; 2-Fluoro-3-pyridyl cyanide
EINECS	Contact for details

Quality Control

Our 3-Cyano-2-Fluoropyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as verified by advanced analytical techniques. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.