Description

Chelerythrine Chloride is a naturally occurring benzophenanthridine alkaloid salt, recognized for its potent and selective inhibitory activity against protein kinase C (PKC). This high-purity biochemical is a critical research tool for studying cellular signaling pathways, apoptosis, and enzyme kinetics. It is essential for pharmaceutical R&D, academic research in biochemistry and pharmacology, and the development of novel therapeutic agents.

Application

• Biochemical Research: A key pharmacological tool for studying Protein Kinase C (PKC) signaling pathways and enzyme inhibition mechanisms.
• Pharmaceutical Development: Used in drug discovery programs targeting cancer, cardiovascular diseases, and neurological disorders where PKC modulation is relevant.
• Apoptosis Studies: Employed in cellular and molecular biology research to investigate programmed cell death and related mechanisms.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Natural Product Chemistry: Used as a marker compound or isolated standard in the study of plant alkaloids and their biological activities.

Basic Information

Product Name	Chelerythrine Chloride
CAS No.	3895-92-9
Molecular Formula	C21H18ClNO4
Molecular Weight	383.82 g/mol
Synonyms	1,2-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium chloride; Toddaline chloride; Chelerythrine chloride; Chelerythrine; 7,8-Dimethoxy-2,3-methylenedioxybenzo[c]phenanthridine chloride
EINECS	223-447-6

Quality Control

Our Chelerythrine Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) confirming identity, purity, and specification compliance is provided with every shipment to ensure it meets the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed immediately after use to prevent degradation from moisture and light exposure.

Specification

Item	Specification
Appearance	Yellow to orange-yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.