Description

Ethyl 3-(Trifluoromethyl)Quinoxaline-2-Carboxylate is a high-value fluorinated heterocyclic building block, specifically a quinoxaline derivative, essential for advanced organic synthesis. Its core value lies in the trifluoromethyl group, which is a critical pharmacophore known to enhance the metabolic stability, lipophilicity, and bioavailability of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by manufacturers of specialty materials and dyes.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the CF3 group improves biological activity and environmental persistence.
• Material Science Precursor: Serves as a building block for advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to the quinoxaline core's electron-deficient properties.
• Dye and Pigment Synthesis: Employed in the creation of specialized fluorinated dyes and pigments with unique colorfastness and optical properties.
• Chemical Biology Probe Development: Utilized as a scaffold for designing molecular probes and inhibitors to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring fluorinated heterocycles.

Basic Information

Product Name	Ethyl 3-(Trifluoromethyl)Quinoxaline-2-Carboxylate
CAS No.	3885-40-3
Molecular Formula	C₁₂H₉F₃N₂O₂
Molecular Weight	270.21 g/mol
Synonyms	Ethyl 3-(trifluoromethyl)-2-quinoxalinecarboxylate; 2-Quinoxalinecarboxylic acid, 3-(trifluoromethyl)-, ethyl ester; 3-Trifluoromethylquinoxaline-2-carboxylic acid ethyl ester; Quinoxaline-2-carboxylic acid, 3-(trifluoromethyl)-, ethyl ester; ETQC; Ethyl 3-trifluoromethylquinoxaline-2-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 3-(Trifluoromethyl)Quinoxaline-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.