Description

Benzoic Acid-α-13C is a stable isotope-labeled derivative of benzoic acid, where the carbon atom at the alpha position is the carbon-13 (13C) isotope. This high-purity labeled compound is essential for applications requiring precise internal standards and metabolic pathway tracing, offering unmatched accuracy in quantitative analysis. It is primarily utilized by research institutions, pharmaceutical developers, and analytical laboratories engaged in advanced mass spectrometry, nuclear magnetic resonance (NMR) spectroscopy, and pharmacokinetic studies.

Application

• Internal Standard for Quantitative Analysis: Serves as a critical reference standard in Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Mass Spectrometry (LC-MS) for the accurate quantification of benzoic acid and related compounds in complex matrices.
• Metabolic Pathway Tracing: Used in biomedical and biochemical research to elucidate metabolic pathways and mechanisms of drug action through 13C isotope tracking.
• NMR Spectroscopy Studies: Provides a valuable tool for structural elucidation and dynamic studies in NMR due to the distinct signal of the 13C label.
• Pharmaceutical Research & Development: Employed in drug metabolism and pharmacokinetics (DMPK) studies to monitor the absorption, distribution, metabolism, and excretion (ADME) of new chemical entities.
• Food & Environmental Analysis: Acts as an isotopic tracer in studies investigating preservative metabolism, environmental fate, and residue analysis of benzoic acid.
• Stable Isotope Labeling for Chemical Synthesis: Used as a building block in the synthesis of more complex 13C-labeled molecules for research purposes.

Basic Information

Product Name	Benzoic Acid-α-13C
CAS No.	3880-99-7
Molecular Formula	C6H513COOH
Molecular Weight	123.11 g/mol (for 13C1 isotopologue)
Synonyms	Benzoic-α-13C Acid; 13C1-Benzoic Acid; Carboxyl-13C Benzoic Acid; Phenyl-13C-carboxylic Acid; Benzenecarboxylic-α-13C Acid; [13C]Carboxybenzene; (Carboxy-13C)benzoic Acid; Benzoic Acid (1-13C)
EINECS	Contact for details

Quality Control

Our Benzoic Acid-α-13C is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity, critical for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and identity confirmation. We adhere to rigorous in-house standards designed for research and analytical use, with capabilities to meet specific customer requirements for isotopic purity and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment (13C)	≥ 99 atom %
Chemical Purity (HPLC)	≥ 98.0%
Melting Point	121 - 123 °C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.