Description

n-Methylacetamide-Oxotremorine M is a specialized cholinergic agonist and research chemical of significant interest in neuroscience and pharmacology. This compound is valued for its high biological activity and specificity in muscarinic receptor studies. It is primarily utilized by pharmaceutical researchers, academic institutions, and R&D laboratories focused on neurodegenerative disease models, cognitive function, and the development of novel therapeutic agents.

Application

• Neuroscience Research: A key tool compound for studying muscarinic acetylcholine receptor (mAChR) subtypes, particularly M1 and M4, in vitro and in vivo.
• Pharmacological Studies: Used to investigate cholinergic pathways, signal transduction, and receptor activation mechanisms relevant to cognitive processes.
• Drug Discovery: Serves as a reference standard and active pharmacophore in the development of new treatments for Alzheimer's disease, Parkinson's disease, and other neurological disorders.
• Biochemical Assays: Employed in high-throughput screening (HTS) and functional assays to evaluate the efficacy and potency of new chemical entities targeting the cholinergic system.
• Academic & Institutional R&D: Essential for university and government research programs exploring fundamental neurobiology and the pathophysiology of cholinergic dysfunction.

Basic Information

Product Name	n-Methylacetamide-Oxotremorine M
CAS No.	3854-07-7
Molecular Formula	C9H18N2O2
Molecular Weight	186.25 g/mol
Synonyms	Oxotremorine M; N-Methyl-N-(1-methyl-4-pyrrolidin-2-ylbutynyl)acetamide; McN-A-343 analog; (R)-N-Methyl-N-(1-methyl-4-(pyrrolidin-2-yl)but-2-ynyl)acetamide; Oxotremorine-M; Cholinergic agonist M1; 3854-07-7
EINECS	Contact for details

Quality Control

Our n-Methylacetamide-Oxotremorine M is produced under strict quality management systems to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation, purity assessment, and impurity profiling. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your regulatory and documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.