Description

Methylamine-15N Hydrochloride is a stable, isotopically labeled salt of methylamine, where the nitrogen atom is the stable isotope nitrogen-15. This compound is essential for advanced research and analytical applications requiring precise isotopic tracing and quantification. It is primarily utilized by scientists and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors for applications such as metabolic pathway studies, NMR spectroscopy, and the synthesis of labeled compounds.

Application

• NMR Spectroscopy & Mass Spectrometry: Serves as a crucial internal standard and reference material for quantitative analysis and structural elucidation.
• Metabolic & Pharmacokinetic Studies: Used as a tracer to study drug metabolism, biochemical pathways, and protein interactions in vivo and in vitro.
• Synthesis of Isotopically Labeled Compounds: Acts as a key building block for synthesizing more complex nitrogen-15 labeled intermediates, active pharmaceutical ingredients (APIs), and agrochemicals.
• Proteomics & Stable Isotope Labeling (SIL): Employed in quantitative proteomics workflows for accurate protein and peptide quantification.
• Environmental & Geochemical Tracing: Applied in research to track nitrogen cycles and transformations in environmental systems.
• Quality Control & Method Development: Used in analytical laboratories to develop, validate, and calibrate sensitive detection methods.

Basic Information

Product Name	Methylamine-15N Hydrochloride
CAS No.	3852-22-0
Molecular Formula	CH315NH2•HCl
Molecular Weight	68.52 g/mol
Synonyms	Methylamine-15N hydrochloride; [15N]Methylamine hydrochloride; Monomethylamine-15N hydrochloride; Methanamine-15N hydrochloride; Aminomethane-15N hydrochloride; 15N-Labeled methylamine HCl; Methylamine hydrochloride (N-15); (15N)Methylamine HCl
EINECS	223-355-1

Quality Control

Our Methylamine-15N Hydrochloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR and mass spectrometry, to confirm isotopic enrichment, chemical purity, and identity. A detailed Certificate of Analysis (COA) is provided, specifying the isotopic purity (atom % 15N) and chemical assay. We ensure compliance with the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 98.0%
Isotopic Purity (15N)	≥ 98 atom % 15N
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.