Description

4-Fluorobenzyl Iodide is a versatile organoiodine building block characterized by its reactive benzyl iodide and para-fluorine substituents. This compound is essential for introducing the 4-fluorobenzyl moiety into complex molecular architectures, enabling the synthesis of advanced intermediates. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for applications ranging from drug discovery to specialty polymer synthesis.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing molecules with fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the fluorobenzyl group enhances biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of fluorinated organic electronic materials for displays and lighting.
• Cross-Coupling Reactions: Acts as an electrophile in various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) to form carbon-carbon bonds.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands and organocatalysts for asymmetric synthesis.
• Fluorine-18 Labeling Precursor: Potential use as a precursor in radiochemistry for Positron Emission Tomography (PET) tracer development.
• Polymer Modification: Used to incorporate fluorinated aromatic units into polymers to alter thermal, chemical, or surface properties.
• General Organic Synthesis: A versatile alkylating agent for nucleophilic substitution reactions in research and fine chemical production.

Basic Information

Product Name	4-Fluorobenzyl Iodide
CAS No.	3831-29-6
Molecular Formula	C7H6FI
Molecular Weight	236.03 g/mol
Synonyms	1-(Iodomethyl)-4-fluorobenzene; (4-Fluorophenyl)methyl Iodide; α-Iodo-4-fluorotoluene; p-Fluorobenzyl Iodide; 4-Fluorobenzyl Iodide; 4-Fluorobenzyl iodide; 4-Fluorobenzyl iodide, 98%; 4-Fluorobenzyl iodide, 97%
EINECS	223-333-5

Quality Control

Our 4-Fluorobenzyl Iodide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality commitment ensures the material is suitable for demanding applications in research and cGMP-compliant synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or otherwise opaque.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.