Description

4-(Trifluoromethyl)Pyridine is a versatile fluorinated heterocyclic building block essential for advanced chemical synthesis. Its unique structure, featuring a pyridine ring substituted with a highly electronegative trifluoromethyl group, makes it a critical intermediate for introducing fluorine atoms into target molecules. This compound is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and material science industries to develop novel active ingredients and functional materials with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the CF₃ group can improve metabolic stability and lipophilicity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science: Incorporated into the design of liquid crystals, organic semiconductors, and polymers to modify electronic properties and stability.
• Chemical Research: Employed in academic and industrial R&D for exploring new fluorination methodologies and constructing complex molecular architectures.

Basic Information

Product Name	4-(Trifluoromethyl)Pyridine
CAS No.	3796-24-5
Molecular Formula	C₆H₄F₃N
Molecular Weight	147.10 g/mol
Synonyms	4-(Trifluoromethyl)pyridine; γ-Trifluoromethylpyridine; 4-Pyridyl trifluoromethane; 4-Trifluoromethylpyridine; Pyridine, 4-(trifluoromethyl)-; 4-CF3-Pyridine; α,α,α-Trifluoro-p-picoline; p-(Trifluoromethyl)pyridine
EINECS	223-269-5

Quality Control

Our 4-(Trifluoromethyl)Pyridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support our clients' regulatory needs and can supply material suitable for research and development under cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.