Description

L-Asparatic Acid-15N is a stable isotope-labeled form of the amino acid L-aspartic acid, where the nitrogen atom is enriched with the 15N isotope. This product is essential for advanced research and development, providing a critical tracer for metabolic pathway analysis, protein structure determination, and NMR spectroscopy studies. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in proteomics, metabolomics, and drug discovery.

Application

• NMR Spectroscopy: Used as an internal standard and tracer for studying protein dynamics, folding, and molecular interactions.
• Metabolic Pathway Analysis: Enables precise tracking of nitrogen incorporation in amino acid and nucleotide biosynthesis studies.
• Proteomics Research: Facilitates quantitative mass spectrometry (MS) for protein identification and turnover rate measurements.
• Drug Discovery & Development: Serves as a labeled precursor in the synthesis of isotopically labeled drug candidates for pharmacokinetic studies.
• Biochemical Assays: Acts as a substrate or standard in enzymatic assays and metabolic flux analysis.
• Nutritional Science Research: Employed in studies investigating amino acid metabolism and nitrogen balance.

Basic Information

Product Name	L-Asparatic Acid-15N
CAS No.	3715-16-0
Molecular Formula	C₄H₇¹⁵NO₄
Molecular Weight	134.10 g/mol (for ¹⁵N labeled form)
Synonyms	(2S)-2-Aminobutanedioic acid-¹⁵N; L-Aspartic acid-¹⁵N; (S)-Aminosuccinic acid-¹⁵N; Aspartic acid-¹⁵N (L-form); H-Asp-OH-¹⁵N; ¹⁵N-L-Aspartic acid; ¹⁵N-L-Asp
EINECS	Contact for details

Quality Control

Our L-Asparatic Acid-15N is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for chemical and isotopic purity, NMR for structural confirmation, and MS for isotopic enrichment verification. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Enrichment (¹⁵N)	≥ 98 atom % ¹⁵N
Optical Rotation	+24.5° to +26.0° (c=1 in 5N HCl)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.