Description

7-Ethoxyresorufin n-Oxide is a high-purity biochemical reagent and a key intermediate in the synthesis of resorufin derivatives. This compound is of significant value in research and development for its role as a precursor to specific fluorogenic substrates used in enzymatic assays. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on cytochrome P450 enzyme studies and high-throughput screening applications.

Application

• Biochemical Research: Critical intermediate in the synthesis of 7-ethoxyresorufin, a standard fluorogenic substrate for measuring CYP1A1/1A2 (ethoxyresorufin-O-deethylase or EROD) activity.
• Enzyme Assay Development: Used in the development and validation of sensitive in vitro assays for drug metabolism and toxicology studies.
• Pharmaceutical Screening: Serves as a key building block for probes used in high-throughput screening (HTS) to identify enzyme inducers or inhibitors.
• Toxicology & Environmental Monitoring: Employed in research models to assess the induction of cytochrome P450 enzymes by xenobiotics and environmental pollutants.
• Diagnostic Reagent Manufacturing: Used in the production of specialized reagents for clinical and research diagnostics related to liver function and metabolic capacity.
• Academic Research: A valuable tool for graduate and post-doctoral research in biochemistry, molecular pharmacology, and chemical biology.

Basic Information

Product Name	7-Ethoxyresorufin n-Oxide
CAS No.	3705-80-4
Molecular Formula	C₁₄H₁₁NO₄
Molecular Weight	257.24 g/mol
Synonyms	7-Ethoxy-3H-phenoxazin-3-one 10-oxide; Ethoxyresorufin N-oxide; 7-Ethoxy-3H-phenoxazin-3-one 10-oxide; Resorufin, 7-ethoxy-, N-oxide; 7-Ethoxyresorufin N-Oxide; EROD Precursor; 7-ER-N-Oxide
EINECS	Contact for details

Quality Control

Our 7-Ethoxyresorufin n-Oxide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical production to support your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Orange to red powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.