Description

Temazepam Glucuronide is a major, pharmacologically inactive metabolite of the benzodiazepine drug temazepam, formed via glucuronidation in the liver. This reference standard is critically important for analytical and forensic laboratories conducting drug metabolism studies, toxicological screenings, and pharmacokinetic research. It is an essential compound for pharmaceutical R&D, clinical diagnostics, and regulatory compliance testing, enabling precise quantification and confirmation of temazepam use.

Application

• Pharmaceutical Reference Standard: Primary use as a certified reference material (CRM) for the quantitative analysis of temazepam and its metabolites in biological matrices.
• Forensic Toxicology: Critical for confirmatory testing in workplace drug testing, post-mortem analysis, and driving under the influence (DUI) cases.
• Drug Metabolism & Pharmacokinetics (DMPK): Used in studies to understand the metabolic pathways, clearance rates, and excretion profiles of temazepam.
• Clinical Research: Employed in developing and validating bioanalytical methods for therapeutic drug monitoring (TDM) and clinical trial sample analysis.
• Quality Control in Manufacturing: Serves as a system suitability standard in the quality control of temazepam active pharmaceutical ingredient (API) and finished dosage forms.
• Academic Research: Utilized in university and institutional research focused on benzodiazepine pharmacology, analytical chemistry techniques, and biomarker discovery.

Basic Information

Product Name	Temazepam Glucuronide
CAS No.	3703-53-5
Molecular Formula	C₂₄H₂₇ClN₂O₈
Molecular Weight	506.93 g/mol
Synonyms	Temazepam O-Glucuronide; 7-Chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one 3-O-β-D-Glucopyranosiduronic Acid; Temazepam β-D-Glucuronide; Temazepam 3-Glucuronide; Temazepam Glucuronide Metabolite; Temazepam Metabolite (Glucuronide); Temazepam Glucuronide Standard
EINECS	Contact for details

Quality Control

Our Temazepam Glucuronide is produced and handled under strict quality management protocols. Each batch is subjected to rigorous identity confirmation, purity analysis, and stability testing using advanced analytical techniques such as HPLC, LC-MS, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical results is provided with every shipment to ensure full traceability and compliance with your research or quality control requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or Certificate of Analysis. For long-term storage, consider storing at -20°C. Keep the container in a dry, well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.