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Vinylmagnesium Chloride CAS NO 3536-96-7


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CAS No.:3536-96-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Vinylmagnesium Chloride is a highly reactive Grignard reagent, widely recognized for its pivotal role in carbon-carbon bond formation. Its primary value lies in its ability to efficiently introduce a vinyl group into a diverse range of electrophiles, serving as a critical building block in complex organic synthesis. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to create key intermediates for active ingredients and specialty polymers.

Application

  • Pharmaceutical Intermediate Synthesis: Key reagent for constructing vinyl-substituted frameworks in active pharmaceutical ingredients (APIs) and drug candidates.
  • Agrochemical Manufacturing: Used in the production of herbicides, fungicides, and insecticides that require vinyl functional groups for bioactivity.
  • Polymer & Material Science: Serves as a monomer or co-monomer precursor in the development of specialty polymers, coatings, and functional materials.
  • Fine Chemical Production: Employed in the synthesis of complex organic molecules, flavors, fragrances, and liquid crystals.
  • Cross-Coupling Reactions: A vital component in Negishi, Kumada, and other transition metal-catalyzed cross-coupling methodologies.
  • Academic & Industrial R&D: Fundamental reagent in exploratory chemistry for developing new synthetic routes and methodologies.

Basic Information

Product Name Vinylmagnesium Chloride
CAS No. 3536-96-7
Molecular Formula C2H3ClMg
Molecular Weight 86.80 g/mol
Synonyms Chloro(vinyl)magnesium; Ethenylmagnesium Chloride; Magnesium, chloroethenyl-; Vinylmagnesium chloride solution; Grignard reagent, vinylmagnesium chloride; Chlorovinylmagnesium; (Chloromagnesio)ethene; Vinyllithium (common related compound)
EINECS 222-576-4

Quality Control

Our Vinylmagnesium Chloride is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as concentration, titrant, and impurity profiles. We adhere to cGMP principles where applicable, and our quality management system is designed to meet the rigorous demands of pharmaceutical and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and pyrophoric nature, this product must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for solutions. Keep away from moisture, heat, and incompatible materials such as strong acids, oxidizers, and protic solvents.

Specification

Item Specification
Appearance Clear, colorless to light yellow solution
Concentration (in THF or Ether) Typically 1.0 M or 1.6 M
Assay (Titration) ≥ 95%
Identification (IR) Conforms
Water Content (Karl Fischer) ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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