Description

Chloromethanesulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as a sulfonylation and chlorosulfonylation reagent, enabling the efficient introduction of the chloromethanesulfonyl functional group. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs, including diuretics, anticonvulsants, and protease inhibitors.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides that incorporate sulfonylurea or sulfonamide moieties.
• Polymer Modification: Acts as a functionalizing agent to introduce sulfonyl chloride groups into polymers for enhanced properties or further chemical reactions.
• Dye and Pigment Manufacturing: Intermediate in the creation of sulfonated dyes and colorants.
• Chemical Research & Development: A valuable reagent for constructing complex molecular architectures in medicinal chemistry and material science.
• Cross-coupling Reactions: Employed in palladium-catalyzed reactions to create carbon-sulfur bonds.

Basic Information

Product Name	Chloromethanesulfonyl Chloride
CAS No.	3518-65-8
Molecular Formula	C2H4Cl2O2S
Molecular Weight	162.99 g/mol
Synonyms	Chloromethanesulfonyl chloride; Methanesulfonyl chloride, chloro-; Chloromethylsulfonyl chloride; NSC 403058; α-Chloromethanesulfonyl chloride; (Chloromethyl)sulfonyl chloride; 1-Chloromethanesulfonyl chloride
EINECS	222-506-8

Quality Control

Our Chloromethanesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of industrial and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.