Description

2,3,6-Trifluoropyridine is a versatile fluorinated heterocyclic building block of significant importance in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms, which enables precise modulation of electronic properties, lipophilicity, and metabolic stability in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for developing active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and oncology.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a backbone for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the development of advanced organic electronic materials, such as semiconductors and liquid crystals.
• Fluorine Chemistry Research: A valuable substrate for studying nucleophilic aromatic substitution and other fluorination reactions.
• Custom Synthesis and Contract Manufacturing: Supplied for bespoke R&D projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2,3,6-Trifluoropyridine
CAS No.	3512-18-3
Molecular Formula	C5H2F3N
Molecular Weight	133.07 g/mol
Synonyms	2,3,6-Trifluoropyridine; Pyridine, 2,3,6-trifluoro-; 2,3,6-Trifluoro-pyridine; 3512-18-3; NSC 406906; AI3-26045; Trifluoropyridine (mixed isomers); 2,3,6-Trifluoropyridine (principal component)
EINECS	Contact for details

Quality Control

Our 2,3,6-Trifluoropyridine is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical properties is provided with each shipment to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.