Description

2,4,6-Trifluoropyridine is a versatile fluorinated heterocyclic building block of significant importance in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms on the pyridine ring, which profoundly influences the molecule's electronic properties, metabolic stability, and lipophilicity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients with enhanced performance profiles.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in creating molecules with improved bioavailability and metabolic resistance.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to efficacy and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science: Employed in the synthesis of fluorinated polymers, liquid crystals, and electronic materials that require specific dielectric properties.
• Chemical Research: A valuable reagent for medicinal chemistry programs, fragment-based drug discovery, and structure-activity relationship (SAR) studies.
• Fluorine Chemistry: Acts as a model substrate for studying nucleophilic aromatic substitution reactions in fluorinated heterocycles.

Basic Information

Product Name	2,4,6-Trifluoropyridine
CAS No.	3512-17-2
Molecular Formula	C5H2F3N
Molecular Weight	133.07 g/mol
Synonyms	2,4,6-Trifluoropyridine; Pyridine, 2,4,6-trifluoro-; 2,4,6-Trifluoropyridin; 2,4,6-Trifluoropyridina; 2,4,6-Trifluoropyridinum; 2,4,6-Trifluoropyridyne; 2,4,6-Trifluoropyridyl; 2,4,6-Trifluoropyridine (CAS 3512-17-2)
EINECS	Contact for details

Quality Control

Our 2,4,6-Trifluoropyridine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with your specified requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.