Description

Adenosine 5'-Monophosphate, Monoanhydride With (Phosphonomethyl)Phosphonic Acid is a specialized nucleotide derivative that serves as a key intermediate in advanced biochemical synthesis and pharmaceutical research. This compound is valued for its unique structure, which combines a nucleotide monophosphate with a bisphosphonate moiety, enabling its use in the development of novel bioactive molecules and enzyme inhibitors. It is primarily sought by research institutions and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications in drug discovery, biochemical tool development, and as a precursor for nucleotide-based therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of nucleotide analogs and prodrugs with potential antiviral or anticancer activity.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for kinases, phosphatases, and other phosphotransferase enzymes.
• Probe Development: Acts as a precursor for labeled compounds (e.g., fluorescent or radioactive tags) used in molecular biology and diagnostic assays.
• Metabolic Pathway Studies: Employed to investigate adenosine-related metabolic pathways and energy transfer mechanisms within cells.
• Material Science: Potential use in the development of functionalized surfaces or biomaterials due to its phosphate groups.

Basic Information

Product Name	Adenosine 5'-Monophosphate, Monoanhydride With (Phosphonomethyl)Phosphonic Acid
CAS No.	3469-78-1
Molecular Formula	C11H17N5O11P2
Molecular Weight	449.23 g/mol
Synonyms	Adenosine 5'-(monohydrogen phosphate) monoanhydride with (phosphonomethyl)phosphonic acid; P1-(5'-Adenosyl)-P2-[(phosphonomethyl)] diphosphate; Adenosine-5'-monophospho-(phosphonomethyl)phosphonic anhydride; AMP-CP; α,β-Methylene-ATP precursor; Adenylyl (phosphonomethyl)phosphonate; NSC 146925
EINECS	Contact for details

Quality Control

Our Adenosine 5'-Monophosphate, Monoanhydride With (Phosphonomethyl)Phosphonic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production standards. Custom synthesis and specific purity grades (e.g., >95%, >98%) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.