Description

Prostaglandin E1 Methyl Ester is a chemically modified derivative of the potent bioactive lipid mediator, Prostaglandin E1 (Alprostadil). This methyl ester form offers enhanced stability and altered pharmacokinetic properties, making it a valuable intermediate and research tool. It is primarily utilized in pharmaceutical research and development, particularly in the study of vascular biology, inflammation, and as a precursor for synthesizing other prostaglandin analogs. This compound is essential for researchers and manufacturers in the life sciences and fine chemical sectors.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of advanced prostaglandin-based therapeutics and analogs.
• Biochemical Research: Used as a standard or probe in studies investigating prostaglandin receptor (EP) signaling pathways and their physiological roles.
• Vascular Biology Studies: Employed in research models to study vasodilation, platelet aggregation inhibition, and endothelial cell function.
• Inflammation Research: Applied in vitro and in vivo to modulate inflammatory responses and study the mechanisms of anti-inflammatory agents.
• Cell Culture & Differentiation: Utilized in specialized cell culture media to influence cellular processes like proliferation and differentiation.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Prostaglandin E1 Methyl Ester
CAS No.	3434-33-1
Molecular Formula	C₂₁H₃₄O₅
Molecular Weight	366.49 g/mol
Synonyms	PGE1 Methyl Ester; Alprostadil Methyl Ester; Methyl (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oate; Methyl 11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oate; 9-Oxo-11α,15S-dihydroxyprosta-5,13-dien-1-oic Acid Methyl Ester; Prostaglandin E1 ME
EINECS	Contact for details

Quality Control

Our Prostaglandin E1 Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and specific tests for residual solvents and related substances. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.