Description

1,2,4,5-Tetramethyl-3-(Trifluoromethyl)Benzene CAS NO 3360-65-4 is a specialized fluorinated aromatic compound characterized by its unique multi-methyl and trifluoromethyl substitution pattern. This structure imparts valuable properties such as enhanced lipophilicity and chemical stability, making it a critical intermediate in advanced chemical synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecules, as well as by manufacturers of specialty materials and liquid crystals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated aromatic cores to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor or a core structure in the production of fluorinated liquid crystals for high-performance displays (LCDs) due to its influence on mesomorphic properties.
• Organic Synthesis & Catalysis: Acts as a versatile reagent or ligand precursor in cross-coupling reactions and organometallic catalysis, leveraging its steric and electronic effects.
• Specialty Polymers & Coatings: Incorporated as a monomer or additive to impart specific characteristics like chemical resistance, low surface energy, or thermal stability to high-performance polymers.
• Research & Development: Employed in academic and industrial R&D for exploring new reaction pathways, material properties, and as a standard in analytical method development.

Basic Information

Product Name	1,2,4,5-Tetramethyl-3-(Trifluoromethyl)Benzene
CAS No.	3360-65-4
Molecular Formula	C11H13F3
Molecular Weight	202.22 g/mol
Synonyms	3-(Trifluoromethyl)durene; Durene, 3-(trifluoromethyl)-; 1,2,4,5-Tetramethyl-3-(trifluoromethyl)benzene; 3-Trifluoromethyldurene; Benzene, 1,2,4,5-tetramethyl-3-(trifluoromethyl)-; α,α,α-Trifluoro-2,3,5,6-tetramethyltoluene; NSC 406925
EINECS	Contact for details

Quality Control

Our production of 1,2,4,5-Tetramethyl-3-(Trifluoromethyl)Benzene adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including GC, HPLC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system is designed to meet the rigorous demands of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is sensitive to strong alkalis and fluorides; keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.