Description

Palmitic Acid-[9,10-3H] is a high-specific-activity, tritium-labeled form of the common saturated fatty acid, palmitic acid. This radiolabeled compound is an indispensable tool for tracing and quantifying metabolic pathways, particularly in lipid biochemistry and metabolic research. It is primarily utilized by researchers in pharmaceutical development, academic institutions, and contract research organizations (CROs) for advanced studies in lipid metabolism, drug discovery, and diagnostic assay development.

Application

• Metabolic Pathway Tracing: Used as a radiotracer to study the β-oxidation, synthesis, and incorporation of fatty acids into complex lipids.
• Drug Discovery & Pharmacology: Employed in in vitro and in vivo assays to evaluate the efficacy of new drug candidates targeting lipid metabolism disorders, such as diabetes or cardiovascular diseases.
• Biochemical Research: Essential for investigating enzyme kinetics (e.g., fatty acid synthase, carnitine palmitoyltransferase) and receptor-ligand interactions related to fatty acid uptake.
• Diagnostic Development: Serves as a key component in the development of radioimmunoassays (RIA) and other diagnostic tests for metabolic conditions.
• Cell Biology Studies: Applied to track cellular uptake, membrane incorporation, and intracellular trafficking of fatty acids.

Basic Information

Product Name	Palmitic Acid-[9,10-3H]
CAS No.	3343-33-7
Molecular Formula	C16H30O2 (³H labeled)
Molecular Weight	~258.4 g/mol (varies with specific activity)
Synonyms	Hexadecanoic Acid-[9,10-3H]; [9,10-3H]-Palmitic Acid; Tritiated Palmitic Acid; ³H-Palmitic Acid; C16:0-[9,10-3H]; Radiolabeled Palmitate; [9,10-³H]Hexadecanoic Acid; Palmitic Acid (tritiated)
EINECS	Contact for details

Quality Control

Every batch of Palmitic Acid-[9,10-3H] is manufactured and analyzed under strict quality systems to ensure radiochemical purity, specific activity, and chemical stability. Comprehensive testing includes analytical techniques such as Radio-HPLC and TLC-radioscanner analysis. A Certificate of Analysis (CoA) detailing specific activity (Ci/mmol or GBq/mmol), radiochemical purity, chemical purity, and solvent composition is provided with each shipment to ensure traceability and compliance with research standards.

Storage

Preserve in a tightly closed container, protected from light. For optimal stability, store at or below -20°C in the original solvent as specified on the label. Store in a designated area for radioactive materials in accordance with local regulations. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Clear, colorless to slightly yellow solution
Identification (HPLC)	Conforms to reference standard
Specific Activity	30-120 Ci/mmol (1.11-4.44 TBq/mmol) [Custom ranges available]
Radiochemical Purity (Radiometric HPLC)	≥ 97%
Chemical Purity (HPLC)	≥ 95%
Solvent	Toluene, Ethanol, or custom solvent system
Concentration	1 mCi/mL (37 MBq/mL) or as specified

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.