Description

Acetoxycycloheximide CAS NO 3326-96-3 is a potent, semi-synthetic derivative of the natural compound cycloheximide, valued for its enhanced biological activity and stability profile. This compound is critical for researchers and manufacturers requiring a reliable and high-purity protein synthesis inhibitor for advanced life science applications. It is primarily utilized in biochemical research, pharmaceutical development, and as a reference standard in analytical laboratories.

Application

• Biochemical Research: As a potent inhibitor of eukaryotic protein synthesis, used to study cellular processes, gene expression, and signal transduction pathways.
• Pharmaceutical Development: Serves as a key intermediate or reference compound in the research and development of novel therapeutic agents, particularly in oncology and anti-fungal studies.
• Agricultural Research: Used in studies investigating plant physiology, fungal growth inhibition, and the development of plant protection agents.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development, validation, and calibration in HPLC and other chromatographic systems.
• Cell Culture & Microbiology: Applied in selective media and experimental protocols to control protein synthesis in eukaryotic cell cultures and study microbial resistance mechanisms.

Basic Information

Product Name	Acetoxycycloheximide
CAS No.	3326-96-3
Molecular Formula	C17H25NO5
Molecular Weight	323.38 g/mol
Synonyms	Naramycin B; Cycloheximide acetate; 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide 4-acetate; 4-Acetoxycycloheximide; Actidione acetate; Actispray; Actidion B; NSC 185
EINECS	222-042-5

Quality Control

Our Acetoxycycloheximide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light and moisture sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.