Description

Phenethylmagnesium Bromide is a versatile organometallic reagent belonging to the Grignard family. It is a critical building block in organic synthesis, valued for its ability to introduce the phenethyl group and act as a strong nucleophile and base. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to construct complex carbon frameworks. Its reactivity makes it indispensable for the formation of carbon-carbon bonds in the production of active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Synthesis: Key intermediate in the production of active pharmaceutical ingredients (APIs), including central nervous system (CNS) drugs and other therapeutic agents.
• Agrochemical Manufacturing: Used in the synthesis of advanced pesticide and herbicide intermediates.
• Fine Chemical Production: Serves as a fundamental reagent for constructing complex organic molecules in research and development laboratories.
• Material Science: Employed in the synthesis of specialty polymers and liquid crystals.
• Nucleophilic Addition Reactions: Reacts with carbonyl compounds (aldehydes, ketones, esters) to form secondary and tertiary alcohols.
• Alkylation Agent: Used for the alkylation of various electrophiles in multi-step synthetic routes.

Basic Information

Product Name	Phenethylmagnesium Bromide
CAS No.	3277-89-2
Molecular Formula	C8H9BrMg
Molecular Weight	209.36 g/mol
Synonyms	Benzeneethanamine, N,N-diethyl-γ-phenylpropylmagnesium bromide; (2-Phenylethyl)magnesium bromide; Phenethylmagnesium bromide solution; Grignard reagent C8H9BrMg; Magnesium, bromo(2-phenylethyl)-; 2-Phenylethylmagnesium bromide
EINECS	221-909-8

Quality Control

Our Phenethylmagnesium Bromide is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as concentration, assay, and impurity profile. Our quality management system is designed to meet the rigorous demands of GMP and ISO standards for advanced synthetic intermediates.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and reacts violently with water. Store under an inert atmosphere (argon or nitrogen) in a cool, dry, well-ventilated area. For solutions, typical recommended storage temperature is 2-8°C. Keep away from heat, sparks, open flames, and incompatible materials such as acids, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance (Solution)	Clear, colorless to light yellow
Concentration (in THF or Ether)	0.5 M - 2.0 M (Custom concentrations available)
Assay (Titration)	≥ 95%
Identification (IR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.