Description

Methanol-14C (5-20 Mci/Mmol) is a carbon-14 radiolabeled compound, specifically a high-specific-activity form of methanol where the carbon atom is the radioactive isotope 14C. This product is essential for precise metabolic pathway tracing, pharmacokinetic studies, and environmental fate analysis in research and development. It is a critical reagent for scientists and quality control professionals in the pharmaceutical, agrochemical, and environmental science industries who require definitive tracking of carbon atoms.

Application

• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Used as a tracer to study the absorption, distribution, metabolism, and excretion (ADME) of new chemical entities and drug candidates.
• Biochemical Pathway Analysis: Employed in fundamental research to elucidate metabolic pathways, such as one-carbon metabolism, in biological systems.
• Environmental Fate and Degradation Studies: Tracks the breakdown and transformation of chemicals and pollutants in soil, water, and air to assess environmental impact.
• Agrochemical Research: Investigates the metabolic pathways of herbicides, pesticides, and plant growth regulators within target organisms and the environment.
• Chemical Synthesis Tracing: Serves as a labeled starting material or intermediate in the synthesis of more complex 14C-labeled compounds for research.
• Quality Control and Reference Standard: Used in analytical laboratories as a reference material for method development and validation in radiochemical analysis.

Basic Information

Product Name	Methanol-14C (5-20 Mci/Mmol)
CAS No.	3046-50-2
Molecular Formula	CH314OH
Molecular Weight	~33.04 g/mol (varies with specific activity)
Synonyms	Carbon-14 Methanol; [14C]Methanol; Methanol (14C); Methyl-14C alcohol; Radiolabeled Methanol; Methanol-C14; 14C-MeOH; Methyl alcohol-14C
EINECS	221-247-9 (for unlabeled Methanol)

Quality Control

Every batch of Methanol-14C is manufactured and analyzed under strict quality systems to ensure identity, purity, and specific activity. Comprehensive release testing includes radiochemical purity (RCP) determination by HPLC and TLC, specific activity verification, and solvent composition analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and relevant Good Manufacturing Practice (GMP) guidelines for radiopharmaceutical precursors.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a dedicated, well-ventilated area at controlled room temperature (15-25°C) or as specified on the label. Store away from sources of ignition and incompatible materials. Follow all applicable local and international regulations for the storage of radioactive materials.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms to reference spectrum
Specific Activity	5 - 20 mCi/mmol
Radiochemical Purity (HPLC)	≥ 98.0%
Chemical Purity (GC)	≥ 99.0%
Solvent (if any)	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.