Description

2-(p-Trifluoromethylbenzyl)-2-Imidazoline is a versatile heterocyclic organic compound featuring a trifluoromethylphenyl substituent. This specialized chemical building block is valued for its unique structural motif, which combines the imidazoline ring's reactivity with the electron-withdrawing and lipophilic properties of the trifluoromethyl group. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands in coordination chemistry and catalysis.
• Material Science Research: Investigated as a monomer or additive for the synthesis of specialty polymers with tailored properties.
• Chemical Biology Probes: Employed in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.

Basic Information

Product Name	2-(p-Trifluoromethylbenzyl)-2-Imidazoline
CAS No.	3038-60-6
Molecular Formula	C11H11F3N2
Molecular Weight	228.21 g/mol
Synonyms	2-[(4-Trifluoromethylphenyl)methyl]-4,5-dihydro-1H-imidazole; 2-[(4-(Trifluoromethyl)benzyl]-2-imidazoline; 2-(4-Trifluoromethylbenzyl)-2-imidazoline; 2-(p-Trifluoromethylbenzyl)imidazolidine; 1H-Imidazole, 4,5-dihydro-2-[[4-(trifluoromethyl)phenyl]methyl]-; 2-(4-Trifluoromethylbenzyl)-4,5-dihydro-1H-imidazole
EINECS	221-242-9

Quality Control

Our production of 2-(p-Trifluoromethylbenzyl)-2-Imidazoline adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory requirements for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.