Description

2,4-Difluoro-1-Vinyl-Benzene is a versatile fluorinated aromatic building block characterized by its vinyl and difluoro substituents. This compound is valued for its role as a key intermediate in advanced organic synthesis, enabling the introduction of a styrenic moiety into complex molecular architectures. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty materials sectors for constructing active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the difluorophenyl group contributes to biological activity and environmental persistence.
• Material Science & Polymer Chemistry: Serves as a monomer or co-monomer for creating specialty polymers, resins, and liquid crystals with tailored thermal, optical, or surface properties.
• Organic Electronics: Employed in the research and development of organic light-emitting diodes (OLEDs) and semiconductors, where fluorinated aromatic units can modify charge transport properties.
• Cross-Coupling Reactions: An excellent substrate for various palladium-catalyzed cross-coupling reactions (e.g., Heck, Suzuki, Sonogashira) due to the reactivity of the vinyl group.
• Chemical Research & Development: A valuable reagent for exploring new synthetic methodologies and constructing complex, fluorinated organic molecules in academic and industrial labs.

Basic Information

Product Name	2,4-Difluoro-1-Vinyl-Benzene
CAS No.	399-53-1
Molecular Formula	C8H6F2
Molecular Weight	140.13 g/mol
Synonyms	1,3-Difluoro-4-vinylbenzene; 2,4-Difluorostyrene; 4-Vinyl-1,3-difluorobenzene; m-Difluorostyrene; Vinyl-2,4-difluorobenzene; 399-53-1; Benzene, 2,4-difluoro-1-vinyl-
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-1-Vinyl-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature: 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.