Description

6-Fluoroindole is a versatile fluorinated heterocyclic building block essential for advanced organic synthesis. Its core value lies in the strategic introduction of a fluorine atom onto the indole scaffold, enabling the fine-tuning of electronic properties, lipophilicity, and metabolic stability in target molecules. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, including kinase inhibitors, serotonin receptor modulators, and other bioactive molecules.
• Agrochemical Research: Building block for developing new generations of herbicides, fungicides, and plant growth regulators with enhanced efficacy and environmental profile.
• Material Science: Used in the creation of organic semiconductors, fluorescent dyes, and advanced polymers where the fluorine atom imparts specific electronic or optical properties.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for designing molecular probes, enzyme inhibitors, and tags for studying biological systems.
• Academic & Contract Research: Fundamental reagent in methodological development and discovery chemistry within university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	6-Fluoroindole
CAS No.	399-51-9
Molecular Formula	C8H6FN
Molecular Weight	135.14 g/mol
Synonyms	6-Fluoro-1H-indole; 1H-Indole, 6-fluoro-; 6-Fluoroindole; 6-FI; 6-Fluorindole; 6-Fluor-1H-indol; 399-51-9; 6-Fluor-indol
EINECS	206-925-6

Quality Control

Our 6-Fluoroindole is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white or light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0% (Standard Grade)
Purity (GC)	≥98.0%
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.