Description

5-Fluoro-2-Nitrobenzaldehyde is a versatile aromatic aldehyde building block characterized by its nitro and fluorine substituents. This compound matters for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for constructing heterocycles and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, especially those containing benzimidazole or quinazoline cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging the bioactivity of the nitro and fluoro groups.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing complex organic dyes and colorants.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions, nucleophilic aromatic substitution, and reductive amination processes.
• Chemical Research & Development: Utilized in academic and industrial labs for method development and exploring new chemical entities.

Basic Information

Product Name	5-Fluoro-2-Nitrobenzaldehyde
CAS No.	395-81-3
Molecular Formula	C7H4FNO3
Molecular Weight	169.11 g/mol
Synonyms	2-Nitro-5-fluorobenzaldehyde; 5-Fluoro-2-nitro-benzaldehyde; 2-Nitro-5-fluorobenzenecarboxaldehyde; 5-Fluoro-2-nitrobenzenecarbaldehyde; Benzaldehyde, 5-fluoro-2-nitro-; 395-81-3; 5-Fluoro-2-nitrobenzaldehyde (technical grade)
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Nitrobenzaldehyde is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized (store under inert atmosphere), it is recommended to handle under an inert atmosphere such as nitrogen for long-term storage and to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Yellow to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	95 - 99 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.