Description

5-Fluoroisoquinoline is a versatile fluorinated heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring a fluorine atom on the isoquinoline scaffold, makes it a critical intermediate for developing novel pharmaceuticals and agrochemicals. This high-purity compound is primarily sought by research institutions and chemical manufacturers in the pharmaceutical, agrochemical, and material science sectors for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used to develop new herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalytic systems and metal-organic frameworks (MOFs).
• Material Science: Acts as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient aromatic system.
• Fluorine Chemistry Studies: A valuable substrate for investigating fluorination reactions and the effects of fluorine substitution on chemical reactivity and physical properties.
• Chemical Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	5-Fluoroisoquinoline
CAS No.	394-66-1
Molecular Formula	C9H6FN
Molecular Weight	147.15 g/mol
Synonyms	Isoquinoline, 5-fluoro-; 5-Fluoro-isoquinoline; 5-Fluoroisoquinoline; 394-66-1; 5-Fluoro-2-azanaphthalene; 5-Fluoro-benzo[f]quinoline; NSC 404087; 5-Fluoroisoquinolin
EINECS	Contact for details

Quality Control

Our 5-Fluoroisoquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles for pharmaceutical intermediates, and our quality systems support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.