Description

2-Fluoro-5-Bromobenzotrifluoride is a high-value fluorinated aromatic building block essential for advanced chemical synthesis. This compound is prized for its unique combination of halogen substituents, which enable precise structural modifications in complex molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic cores.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the fluorine and bromine groups impart specific biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Negishi couplings to form biaryl structures.
• Material Science Research: Employed in the development of advanced polymers and specialty chemicals with tailored properties.
• Chemical Research & Development: A versatile reagent for exploring new synthetic pathways and creating compound libraries in medicinal chemistry.

Basic Information

Product Name	2-Fluoro-5-Bromobenzotrifluoride
CAS No.	393-37-3
Molecular Formula	C7H3BrF4
Molecular Weight	242.99 g/mol
Synonyms	1-Bromo-4-fluoro-2-(trifluoromethyl)benzene; 5-Bromo-2-fluorobenzotrifluoride; 2-Fluoro-α,α,α-trifluoro-5-bromotoluene; 2-Fluoro-5-bromo-α,α,α-trifluorotoluene; 5-Bromo-2-fluorobenzylidene trifluoride; (5-Bromo-2-fluorophenyl)trifluoromethane; Benzene, 1-bromo-4-fluoro-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Bromobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.